Development of a Semi-automatic Digital Imaging System CytoPro for cytogenetic analysis

First computer based imaging system for human chromosome analysis was developed in 1976 (Castleman & Melnyk, 1976). This system was developed for automatic scanning of metaphases and chromosome karyotyping. However, the system was not much used because it lacked the required sensitivity and accuracy. Due to recent developments in the field of microelectronics, imaging and computational power, there is revival of interest in the field of imaging techniques all over the world, to develop and perfect systems for karyotyping and other cytogenetic applications on human and mammalian chromosomes.